Min-protein oscillations in Escherichia coli with spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model

Abstract

We introduce a three-dimensional stochastic reaction-diffusion model to describe MinD/MinE dynamical structures in Escherichia coli. This model spontaneously generates pole-to-pole oscillations of the membrane-associated MinD proteins, MinE ring, as well as filaments of the membrane-associated MinD proteins. Experimental data suggest MinD filaments are two-stranded. In order to model them we assume that each membrane-associated MinD protein can form up to three bonds with adjacent membrane associated MinD molecules and that MinE induced hydrolysis strongly depends on the number of bonds MinD has established.

Corrected typos, changed content

References in corpus (4)

• Dynamic compartmentalization of bacteria: accurate division in E. coli
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• Min-oscillations in Escherichia coli induced by interactions of membrane-bound proteins
• Pattern formation within Escherichia coli: diffusion, membrane attachment, and self-interaction of MinD molecules

Cited by in corpus (5)

• Mobility of Min-proteins in Escherichia coli measured by fluorescence correlation spectroscopy
• Stochastic switching between multistable oscillation patterns of the Min-system
• Predictions from a stochastic polymer model for the MinDE dynamics in E.coli
• Stuttering Min oscillations within E. coli bacteria: A stochastic polymerization model
• Modeling partitioning of Min proteins between daughter cells after septation in Escherichia coli