Coupled dynamics of voltage and calcium in paced cardiac cells

Abstract

We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium.

References in corpus (1)

• Instability and Spatiotemporal Dynamics of Alternans in Paced Cardiac Tissue

Cited by in corpus (4)

• Amplitude equation approach to spatiotemporal dynamics of cardiac alternans
• Indeterminacy of Spatiotemporal Cardiac Alternans
• Spatiotemporal Dynamics of Calcium-Driven Cardiac Alternans
• Traveling ion channel density waves affected by a conservation law