Optical microrheology using rotating laser-trapped particles

Abstract

We demonstrate an optical system that can apply and accurately measure the torque exerted by the trapping beam on a rotating birefringent probe particle. This allows the viscosity and surface effects within liquid media to be measured quantitatively on a micron-size scale using a trapped rotating spherical probe particle. We use the system to measure the viscosity inside a prototype cellular structure.

5 pages, 4 figures. v2: bibliographic details, minor text corrections

References in corpus (6)

• Optical alignment and spinning of laser-trapped microscopic particles
• Optical application and measurement of torque on microparticles of isotropic nonabsorbing material
• Optical torque controlled by elliptical polarization
• Colloidal dynamics in polymer solutions: Optical two-point microrheology measurements
• Optical measurement of microscopic torques
• Orientation of biological cells using plane-polarized Gaussian beam optical tweezers

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