Effect of base-pair inhomogeneities on charge transport along DNA mediated by twist and radial polarons

Abstract

Some recent results for a three--dimensional, semi--classical, tight--binding model for DNA show that there are two types of polarons, named radial and twist polarons, that can transport charge along the DNA molecule. However, the existence of two types of base pairs in real DNA, makes it crucial to find out if charge transport also exist in DNA chains with different base pairs. In this paper we address this problem in its simple case, an homogeneous chain except for a single different base pair, what we call a base-pair inhomogeneity, and its effect on charge transport. Radial polarons experience either reflection or trapping. However, twist polarons are good candidates for charge transport along real DNA. This transport is also very robust with respect to weak parametric and diagonal disorder.

arXiv comment21 pages, 10 figures

References in corpus (8)

• Backbone-induced semiconducting behavior in short DNA wires
• Helicoidal model for DNA opening
• Jet Quenching and the p-bar >= pi- Anomaly at RHIC
• Theoretical study of collective modes in DNA at ambient temperature
• Nonlinear charge transport mechanism in periodic and disordered DNA
• Polarons with a twist
• Charge transport in a nonlinear, three--dimensional DNA model with disorder
• Nonlinear charge transport in DNA mediated by twist modes

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• Tight-binding modeling of charge migration in DNA devices
• Quantum Diffusion in Polaron Model of poly(dG)-poly(dC) and poly(dA)-poly(dT) DNA polymers
• Quasi-periodic and fractal polymers: Energy structure and carrier transfer
• Classical and quantum nonlinear localized excitations in discrete systems