Domain Growth Kinetics in a Cell-sized Liposome

Abstract

We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump. The domain growth process was monitored by fluorescence microscopy, where the growth was mediated by the fusion of domains through the collision. It was found that an average domain size r develops with time t as r ~ t^0.15, indicating that the power is around a half of the theoretical expectation deduced from a model of Brownian motion on a 2-dimensional membrane. We discuss the mechanism of the experimental scaling behavior by considering the elasticity of the membrane.

References in corpus (2)

• Dynamics of Domain Growth in Self-Assembled Fluid Vesicles
• Lateral phase separation in mixtures of lipids and cholesterol systems

Cited by in corpus (6)

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• Coarse-grained molecular dynamics simulation of binary charged lipid membranes: Phase separation and morphological dynamics
• Phase separation and near-critical fluctuations in two-component lipid membranes: Monte Carlo simulations on experimentally relevant scales
• Growth kinetics of circular liquid domains on vesicles by diffusion-controlled coalescence
• Lateral transport of domains in anionic lipid bilayer membranes under DC electric fields: A coarse-grained molecular dynamics study