Chiral separation in microflows
arXiv:cond-mat/0506084 · doi:10.1103/PhysRevLett.96.014502
Abstract
Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology and belongs to the ``Holy Grail'' of organic chemistry. We suggest a new separation technique for chiral molecules that is based on the transport properties in a microfluidic flow with spatially variable vorticity. Because of their size the thermal fluctuating motion of the molecules must be taken into account. These fluctuations play a decisive role in the proposed separation mechanism.
References in corpus (2)
Cited by in corpus (16)
- Artificial Brownian motors: Controlling transport on the nanoscale
- Mechanical separation of chiral dipoles by chiral light
- Separation of microscale chiral objects by shear flow
- Chiral particle separation by a non-chiral micro-lattice
- The role of symmetry in driven propulsion at low Reynolds number
- Exploiting lattice potentials for sorting chiral particles
- Emergence of collective dynamical chirality for achiral active particles
- Computing stationary free-surface shapes in microfluidics
- Chiral Separation by Flows: The Role of Flow Symmetry and Dimensionality
- Accumulating Particles at the Boundaries of a Laminar Flow
- Hydrodynamics of chiral liquids and suspensions
- Constraining the Astrophysical p Process: Cross Section Measurement of the 84Kr(p,g)85Rb Reaction in Inverse Kinematics
- Transport of flexible chiral objects in a uniform shear flow
- Effective aspect ratio of helices in shear flow
- Deterministic transport of particles in a micro-pump
- Tunable Sorting of Mesoscopic Chiral Structures by External Noise in Achiral Periodic Potentials