An Unusual Antagonistic Pleiotropy in the Penna Model for Biological Ageing

Abstract

We combine the Penna Model for biological aging, which is based on the mutation-accumulation theory, with a sort of antagonistic pleiotropy. We show that depending on how the pleiotropy is introduced, it is possible to reproduce both the humans mortality, which increases exponentially with age, and fruitfly mortality, which decelerates at old ages, allowing the appearance of arbitrarily old Methuselah's.

8 pages, 3 figures, to appear in Physica A

References in corpus (1)

• Justification of Sexual Reproduction by Modified Penna Model of Ageing

Cited by in corpus (2)

• A solvable senescence model showing a mortality plateau
• Positive mutations and mutation-dependent Verhulst factor in Penna ageing model