Entropy and Information is Transferred from Peripherical Sites to the Catalytic Sites of Enzymes

Abstract

This research reports the entropy and information transfer throughout seven different enzymatic systems, namely, TIM-Barrel, Human Lysozyme, Ribonuclease A1, Pepsin , b-lactamase, Human Glucokinase and Carbonic anhydrase II. A general trend is detected: entropy and information is transported form the peripherical regions towards the catalytic site of the analyzed enzymatic systems.

arXiv comment26 pages, 4 figures