Isotope Production in Fusion Systems
arXiv:2512.09242
Abstract
Fusion systems producing isotopes via neutron-driven transmutation can achieve economic viability well before reaching energy breakeven. Incorporating carefully selected feedstock materials in a blanket allows fusion systems to generate both electrical power and high-value isotopes, expanding the space of viable concepts, significantly enhancing the economic value of fusion energy, and supporting an accelerated path to adoption. We calculate the value of this co-generation and derive a new economic breakeven condition based on net present value. At lower plasma gain, , high-value transmutation, such as medical radioisotopes, enables pure transmuter fusion systems operating at only watts to megawatts of fusion power: for example, a 3 megawatt system transmuting could fulfill global demand with . At higher gain , it becomes viable to generate electricity in addition to isotopes. For example, co-production of electricity and gold, transmuted from mercury in a fusion blanket, can reduce the required plasma gain for economic viability from - to -. We further highlight techniques to enhance transmutation with asymmetric neutron wall loading. Fusion neutron-driven transmutation therefore offers a revenue-positive pathway for deploying fusion energy at terawatt-scale, starting from smaller watt-to-megawatt-scale machines for radioisotope production and then scaling up to co-producing electricity and gold in larger fusion power plants.
25 pages, 30 figures