Moments Matter: Posterior Recovery in Poisson Denoising via Log-Networks

Abstract

Poisson denoising plays a central role in photon-limited imaging applications such as microscopy, astronomy, and medical imaging. It is common to train deep learning models for denoising using the mean-squared error (MSE) loss, which corresponds to computing the posterior mean $\mathbb{E}[x\mid y]$. When the noise is Gaussian, Tweedie's formula enables approximation of the posterior distribution through its higher-order moments. However, this connection no longer holds for Poisson denoising: while $\mathbb{E}[x\mid y]$ still minimizes MSE, it fails to capture posterior uncertainty. We propose a new strategy for Poisson denoising based on training a log-network. Instead of predicting the posterior mean $\mathbb{E}[x\mid y]$, the log-network is trained to learn $\mathbb{E}[\log x\mid y]$, leveraging the logarithm as a convenient parameterization for the Poisson distribution. We provide a theoretical proof that the proposed log-network enables recovery of higher-order posterior moments and thus supports posterior approximation. Experiments on simulated data show that our method matches the denoising performance of standard MMSE models while providing access to the posterior.