Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals

Abstract

The wavelength and system-resolution dependencies of dynamic optical coherence tomography (DOCT) are investigated experimentally and numerically. Experimental investigations demonstrate significant wavelength dependency for the DOCT values but no resolution dependency. Numerical simulations were performed using diffusion, random-ballistic motion, and mono-directional flow-based motion models. Diffusion and random-ballistic motion-based simulations show significant wavelength dependency. Additionally, small but certain resolution dependency was revealed by these simulations. Mono-directional flow simulations did not show wavelength dependency, but did demonstrate resolution dependency. The DOCT value is sensitive to both tissue dynamics and the OCT system specification. These effects should be considered when interpreting DOCT images.

References in corpus (4)

• Motion artifact removal and signal enhancement to achieve in vivo dynamic full field OCT
• Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging
• Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise
• Optical-coherence-tomography-based deep-learning scatterer-density estimator using physically accurate noise model