Deep Multimodal Fusion of Data with Heterogeneous Dimensionality via Projective Networks
arXiv:2402.01311 · doi:10.1109/JBHI.2024.3352970
Abstract
The use of multimodal imaging has led to significant improvements in the diagnosis and treatment of many diseases. Similar to clinical practice, some works have demonstrated the benefits of multimodal fusion for automatic segmentation and classification using deep learning-based methods. However, current segmentation methods are limited to fusion of modalities with the same dimensionality (e.g., 3D+3D, 2D+2D), which is not always possible, and the fusion strategies implemented by classification methods are incompatible with localization tasks. In this work, we propose a novel deep learning-based framework for the fusion of multimodal data with heterogeneous dimensionality (e.g., 3D+2D) that is compatible with localization tasks. The proposed framework extracts the features of the different modalities and projects them into the common feature subspace. The projected features are then fused and further processed to obtain the final prediction. The framework was validated on the following tasks: segmentation of geographic atrophy (GA), a late-stage manifestation of age-related macular degeneration, and segmentation of retinal blood vessels (RBV) in multimodal retinal imaging. Our results show that the proposed method outperforms the state-of-the-art monomodal methods on GA and RBV segmentation by up to 3.10% and 4.64% Dice, respectively.
Accepted for publication in the IEEE Journal of Biomedical and Health Informatics (JBHI)
References in corpus (5)
- Generalised Dice overlap as a deep learning loss function for highly unbalanced segmentations
- REFUGE Challenge: A Unified Framework for Evaluating Automated Methods for Glaucoma Assessment from Fundus Photographs
- Superhuman Accuracy on the SNEMI3D Connectomics Challenge
- Simultaneous segmentation and classification of the retinal arteries and veins from color fundus images
- Segmentation of Bruch's Membrane in retinal OCT with AMD using anatomical priors and uncertainty quantification