Curvature effects in interfacial acidity of amphiphilic vesicles

Abstract

We analyze the changes in the vicinal acidity (pH) at a spherical amphiphilic membrane. The membrane is assumed to contain solvent accessible, embedded, dissociable, charge regulated moieties. Basing our approach on the linear Debye-Hückel as well as the non-linear Poisson-Boltzmann theory, together with the general Frumkin-Fowler-Guggenheim adsorption isotherm model of the charge regulation process, we analyse and review the dependence of the local pH on the position, as well as bulk electrolyte concentration, bulk pH and curvature of the amphiphilic single membrane vesicle. With appropriately chosen adsorption parameters of the charge regulation model, we find a good agreement with available experimental data.

arXiv comment17 pages, 11 figures

References in corpus (15)

• pH Sensing by Lipids in Membranes: The Fundamentals of pH-driven Migration, Polarization and Deformations of Lipid Bilayer Assemblies
• Role of electrostatic interactions in the assembly of empty spherical viral capsids
• Charge Regulation with Fixed and Mobile Charges
• Electrostatics of Lipid Bilayer Bending
• Ion Induced Lamellar-Lamellar Phase Transition in Charged Surfactant Systems
• Charged Membranes: Poisson-Boltzmann theory, DLVO paradigm and beyond
• Electrostatic interaction between SARS-CoV-2 virus and charged electret fibre
• Charge Regulating Macro-ions in Salt Solutions: Screening Properties and Electrostatic Interactions
• Spontaneous symmetry breaking of charge-regulated surfaces
• Curvature effects in charge-regulated lipid bilayers
• Critical behavior of charge-regulated macro-ions
• Charge regulation radically modifies electrostatics in membrane stacks
• Charge symmetry broken complex coacervation
• Poisson-Boltzmann study of the effective electrostatic interaction between colloids at an electrolyte interface
• Electrostatic pair-interaction of nearby metal or metal-coated colloids at fluid interfaces