Comparison of theoretical approaches for epidemic processes with waning immunity in complex networks

Abstract

The role of waning immunity in basic epidemic models on networks has been undervalued while being noticeable fundamental for real epidemic outbreaks. One central question is which mean-field approach is more accurate in describing the epidemic dynamics. We tackled this problem considering the susceptible-infected-recovered-susceptible (SIRS) epidemic model on networks. Two pairwise mean-field theories, one based on recurrent dynamical message-passing (rDMP) and the other on the pair quenched mean-field theory (PQMF), are compared with extensive stochastic simulations on large networks of different levels of heterogeneity. For waning immunity times longer than or comparable with the recovering time, rDMP outperforms PQMF theory on power-law networks with degree distribution $P(k)\sim k^{-\gamma }$. In particular, for $\gamma >3$, the epidemic threshold observed in simulations is finite, in qualitative agreement with rDMP, while PQMF leads to an asymptotically null threshold. The critical epidemic prevalence for $\gamma >3$ is localized in a finite set of vertices in the case of the PQMF theory. In contrast, the localization happens in a subextensive fraction of the network in rDMP theory. Simulations, however, indicate that localization patterns of the actual epidemic lay between the two mean-field theories, and improved theoretical approaches are necessary to understanding the SIRS dynamics.

10 pages, 4 figures

References in corpus (7)

• Modeling the Worldwide Spread of Pandemic Influenza: Baseline Case and Containment Interventions
• A message passing approach for general epidemic models
• Epidemic thresholds of the Susceptible-Infected-Susceptible model on networks: A comparison of numerical and theoretical results
• Outbreak diversity in epidemic waves propagating through distinct geographical scales
• The localization of non-backtracking centrality in networks and its physical consequences
• High prevalence regimes in the pair quenched mean-field theory for the susceptible-infected-susceptible model on networks
• Simple quasistationary method for simulations of epidemic processes with localized states