Fractional Modelling and Optimal Control of COVID-19 Transmission in Portugal
arXiv:2204.05055 · doi:10.3390/axioms11040170
Abstract
A fractional-order compartmental model was recently used to describe real data of the first wave of the COVID-19 pandemic in Portugal [Chaos Solitons Fractals 144 (2021), Art. 110652]. Here, we modify that model in order to correct time dimensions and use it to investigate the third wave of COVID-19 that occurred in Portugal from December 2020 to February 2021, and that has surpassed all previous waves, both in number and consequences. A new fractional optimal control problem is then formulated and solved, with vaccination and preventive measures as controls. A cost-effectiveness analysis is carried out, and the obtained results are discussed.
This is a preprint of a paper whose final and definite form is published Open Access in 'Axioms' at [https://doi.org/10.3390/axioms11040170]
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