A novel range telescope concept for proton CT

Abstract

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography (pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton's energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7\%. If calorimetric information is used the energy resolution could be further improved to about $0.5\%$. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to $10^8$ protons/s. The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.

References in corpus (10)

• The T2K Experiment
• The T2K Fine-Grained Detectors
• T2K ND280 Upgrade -- Technical Design Report
• A fully active fine grained detector with three readout views
• The SuperFGD Prototype Charged Particle Beam Tests
• Technical Note: A fast and monolithic prototype clinical proton radiography system optimized for pencil beam scanning
• Development of a Depleted Monolithic CMOS Sensor in a 150 nm CMOS Technology for the ATLAS Inner Tracker Upgrade
• Application of large area SiPMs for the readout of a plastic scintillator based timing detector
• Graph neural network for 3D classification of ambiguities and optical crosstalk in scintillator-based neutrino detectors
• A Proton Computed Tomography Demonstrator for Stopping Power Measurements