The Organization of Chaos into a Molecular Trap that Supervises Ligand-Interaction, Selection and Steric Guidance Similar to Events in Black Holes

Abstract

In the current study, we demonstrated that allostery transpires by entropy transfers across time-spatial scales that actualize the conception of a molecular trap that supervises ligand interaction, selection, and migration into the amphipathic groove of the 14-3-3 ζ docking protein. Ligand binding transpires by steric guidance down a multi-dimensional trap constituted of superimposed chaotic, harmonic, and electromagnetic field gradients. The individual traps exist in discrete domains governed by disparate physics interconnected by their resonance states and are subjective to damping. Notably, the highly structured molecular entanglement was genesis by the organization of white noise emitted by the anarchic motion of residues that comprised many of the features of black holes.

23 pages, 17 figures

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