A computational tool to characterize particle tracking measurements in optical tweezers
arXiv:2105.12330 · doi:10.1088/2040-8978/15/8/085701
Abstract
Here we present a computational tool for optical tweezers which calculates the particle tracking signal measured with a quadrant detector and the shot-noise limit to position resolution. The tool is a piece of Matlab code which functions within the freely available Optical Tweezers Toolbox. It allows the measurements performed in most optical tweezers experiments to be theoretically characterized in a fast and easy manner. The code supports particles with arbitrary size, any optical fields and any combination of objective and condenser, and performs a full vector calculation of the relevant fields. Example calculations are presented which show the tracking signals for different particles, and the shot noise limit to position sensitivity as a function of the effective condenser NA.
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