Theory of cell membrane interaction with glass
arXiv:2103.05125 · doi:10.1103/PhysRevE.103.032401
Abstract
There are three regimes of cell membrane interaction with glass - Tight and loose adhesion, separated by repulsion. Explicitly including hydration, this paper evaluates the pressure between the surfaces as functions of distance for ion-correlation and ion-screened electrostatics, and electromagnetic fluctuations. The results agree with data for tight adhesion energy (0.5-3 vs 0.4-4 mJ/m2), detachment pressure (7.9 vs 9 MPa), and peak repulsion (3.4-7.5 vs 5-10 kPa), also matching the repulsion's distance dependence upon renormalization by steric pressure mainly from undulations.