Lateral depletion effect on two-dimensional ordering of bacteriorhodopsins in a lipid bilayer: A theoretical study based on a binary hard-disk model
arXiv:2011.06232 · doi:10.1063/5.0044399
Abstract
The two-dimensional ordering of bacteriorhodopsins in a lipid bilayer was studied using a binary hard-disk model. The phase diagrams were calculated, taking into account the lateral depletion effects. The critical concentrations of the protein ordering for the monomers and the trimers were obtained from the phase diagrams. The critical concentration ratio agreed well with the experiment when the repulsive core interaction between the depletants, namely the lipids, was taken into account. The results suggest that the depletion effect plays an important role in the association behaviors of transmembrane proteins.
arXiv comment12 pages, 4 figures
References in corpus (7)
- Two-step melting in two dimensions: First-order liquid-hexatic transition
- Hard-disk equation of state: First-order liquid-hexatic transition in two dimensions with three simulation methods
- Depletion forces near curved surfaces
- Disappearance of the hexatic phase in a binary mixture of hard disks
- Large Attractive Depletion Interactions in Soft Repulsive-Sphere Binary Mixtures
- Phase Behaviour of Binary Hard-Sphere Mixtures: Free Volume Theory Including Reservoir Hard-Core Interactions
- Phase diagrams and crystal-fluid surface tensions in additive and nonadditive two-dimensional hard disk mixtures