paper

Notes on Exact Power Calculations for t Tests and Analysis of Covariance

arXiv:2001.04013 · doi:10.1080/19466315.2019.1707110

Abstract

Tang derived the exact power formulae for t tests and analysis of covariance (ANCOVA) in superiority, noninferiority and equivalence trials. The power calculation in equivalence trials can be simplified by using Owen's Q function, which is available in standard statistical software. We extend the exact power determination method for ANCOVA to unstratified and stratified multi-arm randomized trials. The method is applied to the design of multi-arm trials and gold standard noninferiority trials.

5 pages