Molecular chains under tension: Thermal and mechanical activation of statistically interacting extension and contraction particles
arXiv:1910.09627 · doi:10.1103/PhysRevE.101.022504
Abstract
This work introduces a methodology for the statistical mechanical analysis of polymeric chains under tension controlled by optical or magnetic tweezers at thermal equilibrium with an embedding fluid medium. The response of single bonds between monomers or of entire groups of monomers to tension is governed by the activation of statistically interacting particles representing quanta of extension or contraction. This method of analysis is capable of describing thermal unbending of the freely jointed or wormlike chain kind, linear or nonlinear contour elasticity, and structural transformations including effects of cooperativity. The versatility of this approach is demonstrated in an application to double-stranded DNA undergoing torsionally unconstrained stretching across three regimes of mechanical response including an overstretching transition. The three-regime force-extension characteristic, derived from a single free-energy expression, accurately matches empirical evidence.
arXiv comment19 pages, 15 figures
References in corpus (11)
- The thermodynamic limit for fractional exclusion statistics
- Thermodynamics of ideal quantum gas with fractional statistics in D dimensions
- Generalized Pauli principle for particles with distinguishable traits
- Taxonomy of particles in Ising spin chains
- Thermodynamics of statistically interacting quantum gas in D dimensions
- Jammed disks in narrow channel: criticality and ordering tendencies
- Coil-helix transition of polypeptide at water-lipid interface
- Statistically interacting vacancy particles
- Statistically interacting quasiparticles in Ising chains
- Disks in a narrow channel jammed by gravity and centrifuge: profiles of pressure, mass density and entropy density
- Interlinking motifs and entropy landscapes of statistically interacting particles
Cited by in corpus (3)
- Jammed disks of two sizes and weights in a channel: Alternating sequences
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- Mechanical response to tension and torque of molecular chains via statistically interacting particles associated with extension, contraction, twist, and supercoiling