Giant Vesicles with Encapsulated Magnetic Nanowires as Versatile Carriers, Transported via Rotating and Non-Homogeneous Magnetic Fields

Abstract

In this work, two real-time methods to transport magnetic nanowires confined in giant hybrid vesi-cles upon the application of different strategies are studied. The microscale carriers are either mag-netically guided through the viscous medium by a non-homogenous field or advected by precisely monitored hydrodynamic flows. The slender geometry of the magnetic component enables the ap-plication of large torques, the in-situ characterization of the rotational dynamics, as well as the guided propulsion via the continuous thrust of the nanowire tip on the confining bilayer. The flexi-bility of the vesicles, required to deform along the steering direction during passage through mi-croscale openings, is enhanced via the adsorption of non-ionic surfactants on the lipid membrane. The resulting integrated system is an excellent candidate to transport colloidal cargos or flu-id amounts of some picoliters in microfluidic platforms, even in physiological environments, since it combines the maneuverability of propelled microscopic systems and the protection conferred by the vesicle.

arXiv comment20 pages, 6 figures, to appear in Particles and Particle Systems Characterization (Wiley)

References in corpus (7)

• Sperm-hybrid micromotor for drug delivery in the female reproductive tract
• Local viscoelasticity of living cells measured by rotational magnetic spectroscopy
• Magnetic Propulsion of Self-Assembled Colloidal Carpets: Efficient Cargo Transport via a Conveyor-Belt Effect
• Magnetic wire-based sensors for the micro-rheology of complex fluids
• Membrane penetration and trapping of an active particle
• Enhancing nanoparticle diffusion on a unidirectional domain wall magnetic ratchet
• Surface microswimmers, harnessing the interface to self-propel