Acoustic scattering mediated single detector optoacoustic tomography

Abstract

Optoacoustic image formation is conventionally based upon ultrasound time-of-flight readings from multiple detection positions. Herein, we exploit acoustic scattering to physically encode the position of optical absorbers in the acquired signals, thus reduce the amount of data required to reconstruct an image from a single waveform. This concept is experimentally tested by including a random distribution of scatterers between the sample and an ultrasound detector array. Ultrasound transmission through a randomized scattering medium was calibrated by raster scanning a light-absorbing microparticle across a Cartesian grid. Image reconstruction from a single time-resolved signal was then enabled with a regularized model-based iterative algorithm relying on the calibration signals. The signal compression efficiency is facilitated by the relatively short acquisition time window needed to capture the entire scattered wavefield. The demonstrated feasibility to form an image using a single recorded optoacoustic waveform paves a way to the development of faster and affordable optoacoustic imaging systems.

arXiv comment4 pages, 3 figures

References in corpus (2)

• Overcoming the acoustic diffraction limit in photoacoustic imaging by localization of flowing absorbers
• Mitigation of artifacts due to isolated acoustic heterogeneities in photoacoustic computed tomography using a variable data truncation-based reconstruction method

Cited by in corpus (4)

• Ultrasound Detection Arrays Via Coded Hadamard Apertures
• The Atomistic Green's Function method for acoustic and elastic wave-scattering problems
• Broadband model-based inversion enables optoacoustic microscopy beyond the acoustic diffraction limit
• Deep Learning Enabled Real-Time Photoacoustic Tomography System via Single Data Acquisition Channel