Enhanced deep detection of Raman scattered light by wavefront shaping
arXiv:1807.10682 · doi:10.1364/OE.26.033565
Abstract
Light scattering limits the penetration depth of non-invasive Raman spectroscopy in biological media. While safe levels of irradiation may be adequate to analyze superficial tissue, scattering of the pump beam reduces the Raman signal to undetectable levels deeper within the tissue. Here we demonstrate how wavefront shaping techniques can significantly increase the Raman signal at depth, while keeping the total irradiance constant, thus increasing the amount of Raman signal available for detection.
References in corpus (10)
- Random-Matrix Theory of Quantum Transport
- Phase control algorithms for focusing light through turbid media
- Universal optimal transmission of light through disordered materials
- Filtering Random Matrices: The Effect of Incomplete Channel Control in Multiple Scattering
- Correlation-enhanced control of wave focusing in disordered media
- Selective coupling of optical energy into the fundamental diffusion mode of a scattering medium
- Measuring large optical reflection matrices of turbid media
- Control of mesoscopic transport by modifying transmission channels in opaque media
- Inverse Design of Perfectly Transmitting Eigenchannels in Scattering Media
- Energy-leaky modes in partially measured scattering matrices of disordered media