Retinal Microaneurysms Detection using Local Convergence Index Features

Abstract

Retinal microaneurysms are the earliest clinical sign of diabetic retinopathy disease. Detection of microaneurysms is crucial for the early diagnosis of diabetic retinopathy and prevention of blindness. In this paper, a novel and reliable method for automatic detection of microaneurysms in retinal images is proposed. In the first stage of the proposed method, several preliminary microaneurysm candidates are extracted using a gradient weighting technique and an iterative thresholding approach. In the next stage, in addition to intensity and shape descriptors, a new set of features based on local convergence index filters is extracted for each candidate. Finally, the collective set of features is fed to a hybrid sampling/boosting classifier to discriminate the MAs from non-MAs candidates. The method is evaluated on images with different resolutions and modalities (RGB and SLO) using five publicly available datasets including the Retinopathy Online Challenge's dataset. The proposed method achieves an average sensitivity score of 0.471 on the ROC dataset outperforming state-of-the-art approaches in an extensive comparison. The experimental results on the other four datasets demonstrate the effectiveness and robustness of the proposed microaneurysms detection method regardless of different image resolutions and modalities.

References in corpus (2)

• An Ensemble-based System for Microaneurysm Detection and Diabetic Retinopathy Grading
• Improved Microaneurysm Detection using Deep Neural Networks

Cited by in corpus (7)

• Gravity Network for end-to-end small lesion detection
• Applications of Deep Learning in Fundus Images: A Review
• A comprehensive survey on computer-aided diagnostic systems in diabetic retinopathy screening
• Automated Detection of Microaneurysms in Color Fundus Images using Deep Learning with Different Preprocessing Approaches
• Pseudo-Labeling for Small Lesion Detection on Diabetic Retinopathy Images
• The Efficacy of Microaneurysms Detection With and Without Vessel Segmentation in Color Retinal Images
• Comparison Different Vessel Segmentation Methods in Automated Microaneurysms Detection in Retinal Images using Convolutional Neural Networks