Quantitative Photoacoustic Imaging of Two-photon Absorption
arXiv:1707.00726 · doi:10.1117/1.JBO.23.1.016002
Abstract
Two-photon absorption photoacoustic tomography (TP-PAT) is a recent hybrid imaging modality that aims at reconstructing two-photon absorption properties of heterogeneous media from measured ultrasound signals generated by the photoacoustic effect. While there have been extensive experimental studies in recent years to show the great promises of TP-PAT, very little has been done on developing computational methods for quantitative image reconstruction in this imaging modality. In this work, we present a mathematical model for quantitative TP-PAT in diffusive media. We implemented a computational strategy for the reconstruction of the optical absorption coefficients, and provide numerical simulations based on synthetic acoustic data to demonstrate the feasibility of quantitative reconstructions in TP-PAT.
References in corpus (8)
- Investigation of iterative image reconstruction in three-dimensional optoacoustic tomography
- Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing
- Time reversal in thermoacoustic tomography - an error estimate
- Quantitative photoacoustic imaging in radiative transport regime
- A one-step reconstruction algorithm for quantitative photoacoustic imaging
- Thermoacoustic tomography with detectors on an open curve: an efficient reconstruction algorithm
- A simple Fourier transform-based reconstruction formula for photoacoustic computed tomography with a circular or spherical measurement geometry
- Inverse transport problems in quantitative PAT for molecular imaging