One-parameter scaling theory for DNA extension in a nanochannel
arXiv:1705.04619 · doi:10.1103/PhysRevLett.119.268102
Abstract
Experiments measuring DNA extension in nanochannels are at odds with even the most basic predictions of current scaling arguments for the conformations of confined semiflexible polymers such as DNA. We show that a theory based on a weakly self-avoiding, one-dimensional "telegraph" process collapses experimental data and simulation results onto a single master curve throughout the experimentally relevant region of parameter space and explains the mechanisms at play.
arXiv commentRevised version. 5 pages, 4 figures, revised version, supplementary information
References in corpus (12)
- Scaling theory of DNA confined in nanochannels and nanoslits
- Effects of electrostatic screening on the conformation of single DNA molecules confined in a nanochannel
- DNA Confined in Nanochannels: Hairpin Tightening by Entropic Depletion
- Fluctuations of a long, semiflexible polymer in a narrow channel
- Nanoconfined circular and linear DNA - equilibrium conformations and unfolding kinetics
- Confined polymers in the extended de Gennes regime
- Extension of nano-confined DNA: quantitative comparison between experiment and theory
- Scaling regimes of a semi-flexible polymer in a rectangular channel
- Orientational correlations in confined DNA
- Bending stiff charged polymers: the electrostatic persistence length
- Monomer distributions and intra-chain collisions of a polymer confined to a channel
- Finite-size corrections for confined polymers in the extended de Gennes regime
Cited by in corpus (4)
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