Cell survival probability in a spread-out Bragg peak for novel treatment planning

Abstract

The problem of variable cell survival probability along the spread-out Bragg peak is one of the long standing problems in planning and optimisation of ion-beam therapy. This problem is considered using the multiscale approach to the physics of ion-beam therapy. The physical reasons for this problem are analysed and understood on a quantitative level. A recipe of solution to this problem is suggested using this approach. This recipe can be used in the design of a novel treatment planning and optimisation based on fundamental science.

6 pages, 3 figures, submitted to EPJD

References in corpus (2)

• Physics of ion beam cancer therapy: a multi-scale approach
• Ion-induced electron production in tissue-like media and DNA damage mechanisms

Cited by in corpus (4)

• Condensed Matter Systems Exposed to Radiation: Multiscale Theory, Simulations, and Experiment
• Phenomenon-based prediction of relative biological effectiveness of ion beams by means of the MultiScale Approach
• Ion-impact-induced multifragmentation of liquid droplets
• Calculation of survival probabilities for cells exposed to high ion fluences