Aspects of the physical principles of the proton therapy with inclusion of nuclear interactions
arXiv:1611.04029
Abstract
The radiotherapy of malignant diseases has reached much progress during the past decade. Thus, intensity modulated radiation therapy (IMRT) and VMAT (Rapidarc) now belong to the standard modalities of tumor treatment with high energy radiation in clinical practice. In recent time, the particle therapy (protons and partially with heavy carbon ions) has reached an important completion of these modalities with regard to some suitable applications. In spite of this enrichment essential features need further research activities and publications in this field: Nuclear reactions and the role of the released neutrons, electron capture of positively charged nuclei at lower projectile energies (e.g. in the environment of the Bragg peak and at the distal end of the particle track), correct dose delivery in scanning methods by accounting for the influence of the lateral scatter of beam-lets. Deconvolution methods can help to overcome these problems, which already occur in radiotherapy of very small photon beams [1 - 8].
arXiv commentPreprint. arXiv admin note: substantial text overlap with arXiv:1008.3645
References in corpus (4)
- Foundation of an analytical proton beamlet model for inclusion in a general proton dose calculation system
- Theoretical methods for the calculation of Bragg curves and 3D distributions of proton beams
- Collimator effects in proton planning
- Characterization of specific nuclear reaction channels by deconvolution in the energy space of the total nuclear cross-section of protons - applications to proton therapy and technical problems (transmutations)