Extension, Torque and Supercoiling in Single, Stretched and Twisted DNA Molecules
arXiv:1606.00408 · doi:10.1063/1.4934988
Abstract
We reinvestigate the model originally studied by Neukirch and Marko that describes the extension, torque and supercoiling in single, stretched and twisted DNA molecules, which consists of a mixture of extended and supercoiled state, using now a more accurate form of the free energy for the untwisted but stretched DNA. The original model uses an approximate form of this free energy and the agreement with experiment is only qualitative. We find that this more accurate free energy significantly improves the results, bring them into quantitative agreement with experiment, throughout the entire force regime. This is rather surprising, considering that the theory is completely parameter-free.
arXiv comment18 pages, 3 figures
References in corpus (6)
- Torsional Directed Walks, Entropic Elasticity, and DNA Twist Stiffness
- Triple minima in free energy of semiflexible polymers
- Apparent Persistence Length Renormalization of Bent DNA
- Inequivalence of Statistical Ensembles in Single Molecule Measurements
- Mechanical response of plectonemic DNA: an analytical solution
- Multi-plectoneme phase of double-stranded DNA under torsion