paper

A Nonparametric Bayesian Technique for High-Dimensional Regression

arXiv:1604.03615 · doi:10.1214/16-EJS1184

Abstract

This paper proposes a nonparametric Bayesian framework called VariScan for simultaneous clustering, variable selection, and prediction in high-throughput regression settings. Poisson-Dirichlet processes are utilized to detect lower-dimensional latent clusters of covariates. An adaptive nonlinear prediction model is constructed for the response, achieving a balance between model parsimony and flexibility. Contrary to conventional belief, cluster detection is shown to be aposteriori consistent for a general class of models as the number of covariates and subjects grows. Simulation studies and data analyses demonstrate that VariScan often outperforms several well-known statistical methods.

arXiv admin note: substantial text overlap with arXiv:1407.5472

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