Long-range attraction of particles adhered to lipid vesicles

Abstract

Many biological systems fold thin sheets of lipid membrane into complex three-dimensional structures. This microscopic origami is often mediated by the adsorption and self-assembly of proteins on a membrane. As a model system to study adsorption-mediated interactions, we study the collective behavior of micrometric particles adhered to a lipid vesicle. We estimate the colloidal interactions using a maximum likelihood analysis of particle trajectories. When the particles are highly wrapped by a tense membrane, we observe strong long-range attractions with a typical binding energy of 150 $k_{B}T$ and significant forces extending a few microns.

References in corpus (5)

• Fluid membranes can drive linear aggregation of adsorbed spherical nanoparticles
• Statistics of Particle Trajectories at Short Time Intervals Reveal fN-Scale Colloidal Forces
• Corrections to the Saffman-Delbruck mobility for membrane bound proteins
• Hydrodynamic Interactions in Two Dimensions
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Cited by in corpus (7)

• Lipid membrane-mediated attractions between curvature inducing objects
• Wrapping of Microparticles by Floppy Lipid Vesicles
• Membrane-Mediated Interactions Between Nonspherical Elastic Particles
• Microparticle assembly pathways on lipid membranes
• Curvature variation controls particle aggregation on fluid vesicles
• Wrapping pathways of anisotropic dumbbell particles by giant unilamellar vesicles
• Membrane-mediated interactions