First passage time distribution in heterogeneity controlled kinetics: going beyond the mean first passage time
arXiv:1510.00932 · doi:10.1038/srep20349
Abstract
The first passage is a generic concept for quantifying when a random quantity such as the position of a diffusing molecule or the value of a stock crosses a preset threshold (target) for the first time. The last decade saw an enlightening series of new results focusing mostly on the so-called mean and global first passage time (MFPT and GFPT, respectively) of such processes. Here we push the understanding of first passage processes a step further. For a simple heterogeneous system we derive rigorously the complete distribution of first passage times (FPTs). Our results demonstrate that the typical FPT significantly differs from the MFPT, which corresponds to the long time behaviour of the FPT distribution. Conversely, the short time behaviour is shown to correspond to trajectories connecting directly from the initial value to the target. Remarkably, we reveal a previously overlooked third characteristic time scale of the first passage dynamics mirroring brief excursion away from the target.
16 pages, 5 figures, IOP LaTeX
References in corpus (7)
- First-passage times in complex scale-invariant media
- State-dependent diffusion: thermodynamic consistency and its path integral formulation
- First passages for a search by a swarm of independent random searchers
- Non-ergodicity, fluctuations, and criticality in heterogeneous diffusion processes
- Collective dynamics effect transient subdiffusion of inert tracers in gel networks
- Helix or Coil? Fate of a Melting Heteropolymer
- Optimization and universality of Brownian search in quenched heterogeneous media
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