Phase diagram of mechanically stretched DNA: The salt effect
arXiv:1409.1724 · doi:10.1016/j.physa.2013.01.029
Abstract
The cations, in form of salt, present in the solution containing DNA play a crucial role in the opening of two strands of DNA. We use a simple non linear model and investigate the role of these cations on the mechanical unzipping of DNA. The Hamiltonian is modified to incoporate the solvent effect and the cations present in the solution. We calculate the melting temperature as well as the critical force that is required to unzip the DNA molecule as a function of salt concentration of the solution. The phase diagrams are found to be in close agreement with the experimental phase diagrams.
References in corpus (19)
- Single-molecule experiments in biological physics: methods and applications
- Single-molecule derivation of salt dependent base-pair free energies in DNA
- Pulling Pinned Polymers and Unzipping DNA
- DNA unzipped under a constant force exhibits multiple metastable intermediates
- Single Molecule Statistics and the Polynucleotide Unzipping Transition
- Theory of Bubble Nucleation and Cooperativity in DNA Melting
- Sequence sensitivity of breathing dynamics in heteropolymer DNA
- Denaturation transition of stretched DNA
- Bubbles and denaturation in DNA
- Breathing dynamics in heteropolymer DNA
- Thermodynamics of Twisted DNA with Solvent Interaction
- Statistical Theory of Force Induced Unzipping of DNA
- Melting of genomic DNA: predictive modeling by nonlinear lattice dynamics
- Statistical physics of the melting of inhomogeneous DNA
- Dependence on temperature and GC content of bubble length distributions in DNA
- Pause Point Spectra in DNA Constant-Force Unzipping
- Effect of defects on thermal denaturation of DNA Oligomers
- Manipulating a single adsorbed DNA for a critical endpoint
- Anharmonic stacking in supercoiled DNA