Maximum therapeutic effect of glioma treatment by radio-frequency electric field
arXiv:1404.7791 · doi:10.1016/j.chaos.2014.11.020
Abstract
An influence of a radio-frequency electric field on glioma - brain cancer development is considered. A specific task emerging here is whether this new medical technology is effective against invasive cells with a high motility, when switching between migrating and proliferating phenotypes takes place. This therapeutic effect is studied in the framework of a continuous time random walk. It is shown that the migration proliferation dichotomy of cancer cells leads to the weakening of the electric field treatment.
Published in Chaos, Solitons & Fractals (2014)