Pore formation phase diagrams for lipid membranes

Abstract

Critical lateral pressure for a pore formation and phase diagram of porous membrane are derived analytically as functions of the microscopic parameters of the lipid chains. The derivation exploits path-integral calculation of the free energy of the ensembles of semi-flexible strings and rigid rods that mimic the hydrophobic tails of lipids in the lipid bilayers and bolalipid membranes respectively. Analytical expressions for the area stretch/compressibility moduli of the membranes are derived in both models.

4 pages, 2 figures, submitted to JETP Letters

References in corpus (2)

• Analytical derivation of thermodynamic properties of bolalipid membrane
• Rupture of a Biomembrane under Dynamic Surface Tension

Cited by in corpus (2)

• Microscopic Description of Thermodynamics of Lipid Membrane at Liquid-Gel Phase Transition
• Area per Lipid in DPPC-Cholesterol Bilayers:Analytical Approach