Improving Photoacoustic-guided Focusing in Scattering Media by Spectrally Filtered Detection

Abstract

We experimentally and numerically study the potential of photoacoustic-guiding for light focusing through scattering samples via wavefront-shaping and iterative optimization. We experimentally demonstrate that the focusing efficiency on an extended absorber can be improved by iterative optimization of the high frequency components of the broadband photoacoustic signal detected with a spherically focused transducer. We demonstrate more than 8-fold increase in the photoacoustic signal generated by a 30 microns wire using a narrow frequency band around 60MHz. We numerically confirm that such optimization leads to a smaller optical focus than using the low frequency content of the photoacoustic feedback.

References in corpus (4)

• Controlling light in scattering media noninvasively using the photo-acoustic transmission-matrix
• Improving visibility in photoacoustic imaging using dynamic speckle illumination
• Light Focusing and Two-Dimensional Imaging Through Scattering Media using the Photoacoustic Transmission-Matrix with an Ultrasound Array
• Nonlinear photoacoustic wavefront shaping (PAWS) for single speckle-grain optical focusing in scattering media

Cited by in corpus (8)

• Roadmap on Wavefront Shaping and deep imaging in complex media
• Light Focusing and Two-Dimensional Imaging Through Scattering Media using the Photoacoustic Transmission-Matrix with an Ultrasound Array
• Microgenetic optimization algorithm for optimal wavefront shaping
• Effect of experimental parameters on optimal reflection of light from opaque media
• Nonlinear photoacoustic wavefront shaping (PAWS) for single speckle-grain optical focusing in scattering media
• Influence of the absorber dimensions on wavefront shaping based on volumetric optoacoustic feedback
• Stability of optimal-wave-front-sample coupling under sample translation and rotation
• Optical wavefront shaping in deep tissue using photoacoustic feedback