Cis-Trans Dynamical Asymmetry in Driven Polymer Translocation

Abstract

During polymer translocation driven by e.g. voltage drop across a nanopore, the segments in the cis-side is incessantly pulled into the pore, which are then pushed out of it into the trans-side. This pulling and pushing polymer segments are described in the continuum level by nonlinear transport processes known, respectively, as fast and slow diffusions. By matching solutions of both sides through the mass conservation across the pore, we provide a physical basis for the cis and trans dynamical asymmetry, a feature repeatedly reported in recent numerical simulations. We then predict how the total driving force is dynamically allocated between cis (pulling) and trans (pushing) sides, demonstrating that the trans-side event adds a finite-chain length effect to the dynamical scaling, which may become substantial for weak force and/or high pore friction cases.

5 pages, 3 figures

References in corpus (8)

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Cited by in corpus (5)

• Local and global dynamics in polypropylene glycol / silica composites
• Driven translocation of a polymer: role of pore friction and crowding
• Using a Péclet Number for the Translocation of Polymer through a Nanopore to Tune Coarse-Grained Simulations to Experimental Conditions
• Reducing the variance in the translocation times by pre-stretching the polymer
• Non-equilibrium effects in chaperone-assisted translocation of a stiff polymer