Scalable, Non-Invasive Glucose Sensor Based on Boronic Acid Functionalized Carbon Nanotube Transistors

Abstract

We developed a scalable, label-free all-electronic sensor for D-glucose based on a carbon nanotube transistor functionalized with pyrene-1-boronic acid. This sensor responds to glucose in the range 1 uM - 100 mM, which includes typical glucose concentrations in human blood and saliva. Control experiments establish that functionalization with the boronic acid provides high sensitivity and selectivity for glucose. The devices show better sensitivity than commercial blood glucose meters and could represent a general strategy to bloodless glucose monitoring by detecting low concentrations of glucose in saliva.

8 pages, 4 figures, to appear in Applied Physics Letters

References in corpus (4)

• Hybrids of a Genetically Engineered Antibody and a Carbon Nanotube Transistor for Detection of Prostate Cancer Biomarkers
• Differentiation of Complex Vapor Mixtures Using Versatile DNA-Carbon Nanotube Chemical Sensor Arrays
• Towards Quantifying the electrostatic transduction mechanism in carbon nanotube molecular sensors
• A Carbon Nanotube Immunosensor for Salmonella