A Mathematical Model for Estimating Biological Damage Caused by Radiation

Abstract

We propose a mathematical model for estimating biological damage caused by low-dose irradiation. We understand that the Linear Non Threshold (LNT) hypothesis is realized only in the case of no recovery effects. In order to treat the realistic living objects, our model takes into account various types of recovery as well as proliferation mechanism, which may change the resultant damage, especially for the case of lower dose rate irradiation. It turns out that the lower the radiation dose rate, the safer the irradiated system of living object (which is called symbolically "tissue" hereafter) can have chances to survive, which can reproduce the so-called dose and dose-rate effectiveness factor (DDREF).

22 pages, 6 Figs, accepted in Journal of the Physical Society of Japan

Cited by in corpus (4)

• Whack-A-Mole Model: Towards unified description of biological effect caused by radiation-exposure
• Reaction Rate Theory of Radiation Exposure and Scaling Hypothesis in Mutation Frequency
• Comparison of data on Mutation Frequencies of Mice Caused by Radiation - Low Dose Model -
• Dose and dose-rate dependence of mutation frequency under long-term exposure - A new look at DDREF from WAM model -