From Physics to Biology by Extending Criticality and Symmetry Breakings

Abstract

Symmetries play a major role in physics, in particular since the work by E. Noether and H. Weyl in the first half of last century. Herein, we briefly review their role by recalling how symmetry changes allow to conceptually move from classical to relativistic and quantum physics. We then introduce our ongoing theoretical analysis in biology and show that symmetries play a radically different role in this discipline, when compared to those in current physics. By this comparison, we stress that symmetries must be understood in relation to conservation and stability properties, as represented in the theories. We posit that the dynamics of biological organisms, in their various levels of organization, are not "just" processes, but permanent (extended, in our terminology) critical transitions and, thus, symmetry changes. Within the limits of a relative structural stability (or interval of viability), variability is at the core of these transitions.

Written for the special issue "Systems Biology and Cancer", edited by Ana Soto and Carlos Sonnenschein; ISSN: 0079-6107

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• Auditory Sensitivity Provided by Self-tuned Critical Oscillations of Hair Cells
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Cited by in corpus (6)

• Modeling mammary organogenesis from biological first principles: Cells and their physical constraints
• Alternative approach to thermodynamic phase transitions
• Time-dependent probability density functions and information geometry in stochastic logistic and Gompertz models
• Far-from-Equilibrium Time Evolution between two Gamma Distributions
• From Logic to Biology via Physics: a survey
• Randomness and Multi-level Interactions in Biology