Thermomechanics of DNA

Abstract

A theory for thermomechanical behavior of homogeneous DNA at thermal equilibrium predicts critical temperatures for denaturation under torque and stretch, phase diagrams for stable B--DNA, supercoiling, optimally stable torque, and the overstretching transition as force-induced DNA melting. Agreement with available single molecule manipulation experiments is excellent.

4 pages, 5 figures. Letter

References in corpus (2)

• Thermal Denaturation of Fluctuating DNA Driven by Bending Entropy
• Thermally Induced Local Failures in Quasi-One-Dimensional Systems: Collapse in Carbon Nanotubes, Necking in Nanowires and Opening of Bubbles in DNA

Cited by in corpus (6)

• Sequence-dependent thermodynamics of a coarse-grained DNA model
• A primer on the oxDNA model of DNA: When to use it, how to simulate it and how to interpret the results
• Coarse-grained simulations of DNA overstretching
• Thermomechanical Stability and Mechanochemical Response of DNA: a Minimal Mesoscale Model
• Mechanical response to tension and torque of molecular chains via statistically interacting particles associated with extension, contraction, twist, and supercoiling
• Quasi-One-Dimensional Thermal Breakage