paper

Exploiting temporal network structures of human interaction to effectively immunize populations

arXiv:1011.3928 · doi:10.1371/journal.pone.0036439

Abstract

If we can lower the number of people needed to vaccinate for a community to be immune against contagious diseases, we can save resources and life. A key to reach such a lower threshold of immunization is to find and vaccinate people who, through their behavior, are more likely to become infected and effective to spread the disease than the average. Fortunately, the very behavior that makes these people important to vaccinate can help us finding them. People you have met recently are more likely to be socially active and thus central in the contact pattern, and important to vaccinate. We propose two immunization schemes exploiting temporal contact patterns. Both of these rely only on obtainable, local information and could implemented in practice. We show that these schemes outperform benchmark protocols in four real data sets under various epidemic scenarios. The data sets are dynamic, which enables us to make more realistic evaluations than other studies - we use information only about the past to perform the vaccination and the future to simulate disease outbreaks. We also use models to elucidate the mechanisms behind how the temporal structures make our immunization protocols efficient.

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