Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches
arXiv:1005.5314 · doi:10.1103/PhysRevLett.104.228102
Abstract
The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling waves, b) moving patches, and c) random fluctuations. Increasing actin concentration causes a transition from patches to waves. The waves and patches move by a treadmilling mechanism which does not require myosin II. The effects of downregulation of key proteins on actin wave behavior are evaluated.
10 pages, 4 figures
References in corpus (2)
Cited by in corpus (5)
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