Force induced melting of the constrained DNA
arXiv:0912.2414 · doi:10.1063/1.3427587
Abstract
We develop a simple model to study the effects of an applied force on the melting of a double stranded DNA (dsDNA). Using this model, we could study the stretching, unzipping, rupture and slippage like transition in a dsDNA. We show that in absence of an applied force, the melting temperature and the melting profile of dsDNA strongly depend on the constrained imposed on the ends of dsDNA. The nature of the phase boundary which separates the zipped and the open state for the shearing like transition is remarkably different than the DNA unzipping
8 pages, 10 figures
References in corpus (10)
- Measurement of the Phase Diagram of DNA Unzipping in the Temperature- Force Plane
- Force-induced desorption of a linear polymer chain adsorbed on an attractive surface
- Complete Phase Diagram of DNA Unzipping: Eye, Y-fork and triple point
- Does changing the pulling direction give better insight into biomolecules?
- Effects of Eye-phase in DNA unzipping
- Force induced triple point for interacting polymers
- An intermediate phase in DNA melting
- Shear Unzipping of DNA
- Dynamics of force-induced DNA slippage
- Role of pulling direction in understanding the energy landscape of proteins
Cited by in corpus (6)
- Force-induced rupture of a DNA duplex
- Coarse-grained simulations of DNA overstretching
- The probability analysis of opening of DNA
- Effect of shear force on the separation of double stranded DNA
- Sufficient minimal model for DNA denaturation: Integration of harmonic scalar elasticity and bond energies
- Temperature phase transition model for the DNA-CNTs-based nanotweezers