Evolution models with base substitutions, insertions, deletions and selection

Abstract

The evolution model with parallel mutation-selection scheme is solved for the case when selection is accompanied by base substitutions, insertions, and deletions. The fitness is assumed to be either a single-peak function (i.e., having one finite discontinuity) or a smooth function of the Hamming distance from the reference sequence. The mean fitness is exactly calculated in large-genome limit. In the case of insertions and deletions the evolution characteristics depend on the choice of reference sequence.

6 pages, 2 figures

References in corpus (1)

• A Solvable Sequence Evolution Model and Genomic Correlations

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