Looking into DNA breathing dynamics via quantum physics

Abstract

We study generic aspects of bubble dynamics in DNA under time dependent perturbations, for example temperature change, by mapping the associated Fokker-Planck equation to a quantum time-dependent Schroedinger equation with imaginary time. In the static case we show that the eigenequation is exactly the same as that of the $\beta$-deformed nuclear liquid drop model, without the issue of non-integer angular momentum. A universal breathing dynamics is demonstrated by using an approximate method in quantum mechanics. The calculated bubble autocorrelation function qualitatively agrees with experimental data. Under time dependent modulations, utilizing the adiabatic approximation, bubble properties reveal memory effects.

5 pages, 1 figure

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Cited by in corpus (3)

• Superaging correlation function and ergodicity breaking for Brownian motion in logarithmic potentials
• Influence of external potentials on heterogeneous diffusion processes
• DNA breathing dynamics: Analytic results for distribution functions of relevant Brownian functionals