Drug-therapy networks and the predictions of novel drug targets

Abstract

Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the effects of drugs on the robustness of cellular networks.

arXiv commentThis is an extended version of the Journal of Biology paper containing 2 Figures, 1 Table and 44 references

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• Structure and dynamics of molecular networks: A novel paradigm of drug discovery. A comprehensive review
• Perturbation waves in proteins and protein networks: Applications of percolation and game theories in signaling and drug design