Drug-therapy networks and the predictions of novel drug targets

Abstract

Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the effects of drugs on the robustness of cellular networks.

This is an extended version of the Journal of Biology paper containing 2 Figures, 1 Table and 44 references

References in corpus (4)

• Hierarchical structure and the prediction of missing links in networks
• The efficiency of multi-target drugs: the network approach might help drug design
• Multiple, weak hits confuse complex systems: A transcriptional regulatory network as an example
• Prediction and verification of indirect interactions in densely interconnected regulatory networks